Behcet’s Syndrome
Behcet's syndrome is an autoimmune inflammatory condition that
can affect different parts of the body. The most common type
results in ulcers in the mouth and/or genital area. Joint pain and
swelling, skin rashes, stomach pains and inflammation of the eyes
can also occur. Rarely the brain, nerves or blood vessels can also
be involved. Historically, Behcet's syndrome was seen along the old
Silk route, e.g. in people with Turkish or Syrian heritage, but it
can also occur in other people.
Management includes treatment to control the inflammation, for
example with topical treatments for ulcers, short courses of oral
prednisolone (steroids) and steroid sparing agents such as
Azathioprine or Colchicine. Patients with inflammation in more than
one body area (e.g inflammation of the eyes and joint swelling) are
often managed by different specialities working together (e.g.
doctors in ophthalmology and rheumatology). There are also three
tertiary Behcet's centres in the UK (Birmingham, Liverpool and
London) who we can discuss with for people with complex problems or
requiring biological medications.
Information for patients:
https://www.vasculitis.org.uk/about-vasculitis/behcets-disease
http://www.behcets.nhs.uk/
Information for clinicians:
http://www.behcets.nhs.uk/
https://ard.bmj.com/content/77/6/808