Criteria and Instructions for Referral of Patients with
Oligometastatic Disease for SABR at Bristol Cancer Institute
Oligometastases (3 sites or
less)
|
Site
|
Currently available at Bristol
|
Comments
|
Lung
|
Yes
|
|
Bone (non spine)
|
Yes
|
|
Spine
|
Yes
|
|
Lymph nodes
|
Yes
|
|
Adrenal
|
Yes
|
|
Liver
|
Yes
|
|
Re-irradiation of pelvis
|
No
|
Available at selected centres
|
General criteria
- Metastatic Cancer with either a histologically or cytologically
proven primary site (or a male patient with PSA>50 and clinical
evidence of prostate cancer)
- 1 - 3 sites of metastatic disease
- Maximum size of any single metastasis of 6cm (5cm for lung or
liver)
- Disease free interval between primary treatment and
development of metastases >6 months
- Life expectancy > 6 months
- Performance status 0 - 2
- Exclude patients who have had previous radiotherapy
within the planned treatment volume
- Prior discussion with disease site specific oncologist
- Prostate/Lung/Breast - once CORE trial open these patients will
not be eligible for CtE
Site Specific criteria
Lung
- Histologically or radiologically confirmed lung metastases
- Not suitable for surgery due to co-morbidities, inadequate lung
function or disease status
- Peripherally located lung metastases (>2cm from radius of
main airways and proximal bronchial tree)
Lymph nodes
- Exclude patients requiring irradiation of whole nodal
field
Adrenal
- Absent or limited and potentially treatable extra-adrenal
disease
- Systemic therapy completed (or discontinued 4 weeks before SABR
started)
Liver
- 1 - 3 liver metastases on contrast enhanced CT and/or MRI
- Unresectable, patient unfit for surgery or presence of
extra-hepatic disease makes surgery inappropriate
- Childs-Pugh Class A
- Adequate hepatic function:
- >700cc normal liver (liver volume-gross tumour volume)
- Bilirubin < 3 x upper limit of normal
- NR < 1.3
- ALT < 5 x upper limit of normal
- Platelets > 80
- Exclude patients with active hepatitis or clinically
significant liver failure, clinically apparent ascites or CNS
metastases
- Patient suitability established at Hepatobiliary MDT prior to
referral
Instructions for referral
Please send your referral letter from
a secure nhs.net email account to the following group email
account:
ubh-tr.SABRteam@nhs.net
Please also send the results of any
relevant tests e.g. lung function, liver function to this
address.
Please make available any recent scans
for the team in Bristol to view.
If you are referring from another
hospital trust please complete an Inter-provider Transfer Form and
email to the above address.
Please complete the relevant SABR referral checklist below:
Any further queries should be directed
via the email account or to:
Dimitra
Kalogianni
SABR Co-ordinator
0117 342 3970
Jancis Kinsman
SABR Lead Radiographer
0117 342 4469
Dr Charles Comins
SABR Clinical Lead
0117 342 3176