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Results - Use of ffDNA in prenatal diagnosis

There have been numerous publications relating to the work conducted by Prof Soothill and colleagues, please follow the links below to find out more:

 

Attilakos G, Maddocks DG, Davies T, Hunt LP, Avent ND, Soothill PW, Grant SR. Quantification of free fetal DNA in multiple pregnancies and relationship with chorionicity. Prenat Diagn. 2011 Oct;31(10):967-72. doi: 10.1002/pd.2814. Epub 2011 Jul 19.

Illanes S, Parra M, Serra R, Pino K, Figueroa-Diesel H, Romero C, Arraztoa JA, Michea L, Soothill PW. Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction. Prenat Diagn. 2009 Dec;29(12):1118-22

Maddocks DG, Alberry MS, Attilakos G, Madgett TE, Choi K, Soothill PW, Avent ND. The SAFE project: towards non-invasive prenatal diagnosis. Biochem Soc Trans. 2009 Apr;37(Pt 2):460-5.

Avent ND, Madgett TE, Maddocks DG, Soothill PW. Cell-free fetal DNA in the maternal serum and plasma: current and evolving applications. Curr Opin Obstet Gynecol. 2009 Apr;21(2):175-9.

Alberry MS, Maddocks DG, Hadi MA, Metawi H, Hunt LP, Abdel-Fattah SA, Avent ND, Soothill PW.Quantification of cell free fetal DNA in maternal plasma in normal pregnancies and in pregnancies with placental dysfunction. Am J Obstet Gynecol. 2009 Jan;200(1):98.e1-6.

Avent ND, Plummer ZE, Madgett TE, Maddocks DG, Soothill PW. Post-genomics studies and their application to non-invasive prenatal diagnosis. Semin Fetal Neonatal Med. 2008 Apr;13(2):91-8.

Alberry MS, Soothill PW.Non-invasive prenatal diagnosis: implications for antenatal diagnosis and management of high-risk pregnancies. Semin Fetal Neonatal Med. 2008 Apr;13(2):84-90

Alberry M, Maddocks D, Jones M, Abdel Hadi M, Abdel-Fattah S, Avent N, Soothill PW. Free  fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast. Prenat Diagn. 2007 May;27(5):415-8.

Illanes S, Denbow M, Kailasam C, Finning K, Soothill PW. Early detection of cell-free fetal DNA in maternal plasma. Early Hum Dev. 2007 Sep;83(9):563-6

Illanes S, Denbow ML, Smith RP, Overton TG, Soothill PW, Finning K. Detection of cell-free fetal DNA in maternal urine. Prenat Diagn. 2006 Dec;26(13):1216-8.

Smith RP, Lombaard H, Soothill PW. The obstetrician's view: ethical and societal implications of non-invasive prenatal diagnosis. Prenat Diagn. 2006 Jul;26(7):631-4.

Illanes S, Avent N, Soothill PW. Cell-free fetal DNA in maternal plasma: an important advance to link fetal genetics to obstetric ultrasound. Ultrasound Obstet Gynecol. 2005 Apr;25(4):317-22.

Bartha JL, Finning K, Soothill PW. Fetal sex determination from maternal blood at 6 weeks of gestation when at risk for 21-hydroxylase deficiency. Obstet Gynecol. 2003 May;101(5 Pt 2):1135-6.