Neuro-endo-immunomodulation in glucocorticoid based therapeutics
Chief Investigator
|
Institution
|
Dates
|
Funding Stream
|
Amount
|
| Dr Georgina Russell |
University of Bristol |
29/02/2020 to 07/12/2021
|
Above and Beyond Neurosciences and Mental Health Legacies
2019
|
£98,205 |
Summary
Steroids are commonly prescribed medications with hundreds and
thousands of people taking them at any moment in time. They are
generally given to treat inflammatory disease such as arthritis.
Some patients also require them because they do not make enough
steroids and so need replacement therapy. Steroids are good
treatments, but patients experience lots of side effects even at
low dosages. It can be difficult to tell the difference between
side effects and the condition that is being treated. Additionally,
long term treatment may cause patients to stop responding as well
to the steroids. The purpose of this project is to be able to
develop a series of projects to better understand steroid side
effects.
Specifically
- To arrange patient groups so we can understand what is
important to people taking steroids and if they would be willing to
try new treatments and ways of recording their experience of
side-effects.
- To fine tune and prove effectiveness of a more natural form of
steroid replacement therapy using a pump.
- To develop new ways of measuring side effects and disease
activity in steroid and steroid sparing treatment in inflammatory
disease.
