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Treatment

After having tests to diagnose and assess oesophageal cancer, your doctor will discuss your treatment options with you. Treatment options are determined at a weekly meeting of specialists where all the test results are discussed. A lot of different people are involved in making these decisions, including surgeons, oncologists (cancer specialists), radiologists (imaging specialists), histopathologists (experts in tissue analysis) and cancer nurse specialists. This meeting is called the 'Multi-Disciplinary Team' (MDT) meeting. This means that the right decisions can be made with you based on the specific details of you and your test results.

In general, the treatment options available are explained below.

Curative-intent vs palliative treatment

Depending upon the results of the tests and the individual patient, treatment may be planned to try and remove all cancer and avoid it coming back (curative-intent treatment). Alternatively, it may not be possible to cure the cancer. For example, it may have already spread to other organs, or it may be too big near the heart or main blood vessels. In this case, treatment is called 'palliative', and is designed to give the best combination of quality and amount of time of survival possible. Even when it is not possible to cure a person of cancer, there is much that the team of doctors and nurses can do to help with symptoms and to support a person and their family.

Chemotherapy

Chemotherapy involves the use of different types of drugs to target cancer. Some medicines are given into the vein and others can be taken as tablets. Often a combination is used. Usually treatment is given over a period of months in a series of cycles, with short breaks between to allow recovery. Chemotherapy may be given as part of a curative-intent regime, with other treatments such as surgery or radiotherapy. It may also be given as treatment when it is not possible to cure cancer, to prolong survival or to improve symptoms (palliative chemotherapy). As with any treatment, there are risks and side effects which your doctor will discuss with you.

Radiotherapy

Radiotherapy involves the use of targeted radiation to treat cancer. This is often done as a course of several treatments which therefore require repeated trips to hospital. As with chemotherapy, radiotherapy may form part of a curative-intent treatment plan, or it may be given to help with symptoms when it is not possible to cure a person's cancer (palliative radiotherapy). Your doctor will discuss the details as well as the risks and benefits of treatment.

Surgery

Surgery for oesophageal cancer forms part of a curative-intent treatment plan, most often in combination with chemotherapy (and sometimes radiotherapy) before and/or after the operation itself. The surgery to remove oesophageal cancer is a major operation, involving surgery on both the abdomen and chest. Only about a third of patients diagnosed with oesophageal cancer undergo surgery. Many people cannot have surgery because their cancer has already spread and it cannot be cured. Other reasons surgery is not possible include cancer involving other major organs that cannot be removed (such as the heart), or a patient may not be fit enough to survive the operation itself.

The operation involves removing most of the oesophagus and part of the top of the stomach. The remaining part of the stomach is made into a tube to replace the oesophagus that has been removed. After the operation, once the new tube has healed in place, you can eat normal food, but in smaller amounts, such that many people need to eat 5-6 smaller meals through the day. It can take up to 9-12 months to fully recover from the operation. Your doctor will tell you more about the risks of the operation, the side effects, and the likely recovery period.

Oesophageal stenting

An oesophageal stent is a tube that can be inserted to hold open the oesophagus. This is done using an endoscope, usually with an injection of a painkiller and sedative (not under a full general anaesthetic). It is a good treatment to improve swallowing when a person cannot have curative treatment. Your doctor can explain more about what is involved as well as any risks of the procedure.

Brachytherapy

Brachytherapy is when radiotherapy is delivered directly into a cancer. For patients with oesophageal cancer that cannot be cured, this treatment can be a very good way of helping improve swallowing if the cancer is suitable. It involves having an endoscopy with sedation. This allows placement of the device that delivers the radiotherapy into the oesophagus. Not every cancer is suitable, so your doctor will explain if this is an option for you. We have created an information leaflet about brachytherapy, which is available by clicking here.