Haemato-oncology
As a Primary Treatment Centre for Paediatric Cancers we offer
treatment for all forms of childhood leukaemia and enter children
into all available late phase (Phase 3) clinical trials for
Leukaemia with appropriate parental consent.
Non-malignant/benign haematology
Bristol Haemophilia Centre:
The Bristol Haemophilia Centre is the designated Comprehensive
Care Centre for all children with haemophilia across the South West
of England. The Centre provides specialist care to adults and
children with heritable bleeding disorders in this region and is
currently increasing in clinical activity by 10% per year with an
annual factor concentrate budget of £6M. The centre achieved formal
designation as a Haemophilia Comprehensive Care centre following
external audit by the UKHCDO in 2007 and in 2012 was commissioned
to provide comprehensive care to all children with haemophilia in
the South West region in a clinical network with local clinicians.
The service provides care to over 150 children with heritable
bleeding disorders including over 40 with severe phenotype
disorders receiving prophylaxis regimes. The centre has full IT
support including access to the Haemophilia Clinical Information
system (HCIS).
Haemoglobinopathies:
Bristol Children's Hospital Sickle Cell and Thalassemia service
is responsible for the care of patients with inherited haemoglobin
disorders locally and throughout the South West region in
collaboration with a number of shared care centres (69 sickle cell
disease and 2 thalassaemia). We offer routine transcranial doppler
screening for children with sickle cell disease who are at
increased risk of stroke.
Haematology Laboratory:
This comprehensive laboratory with full UKAS accreditation
provides the full range of diagnostic facilities required for
tertiary paediatric haematology. It has an annual workload of
354,500 patient requests. The laboratories are staffed by a total
of 25 WTE biomedical scientist and trainee biomedical scientists of
an appropriate skill mix. Histopathology, immunophenotyping,
molecular monitoring of minimal residual disease and cytogenetics
for the diagnosis of paediatric haematological malignancies are
performed at specialist regional laboratories in Southmead
hospital.
Haemostasis laboratory:
The Haemostasis laboratory processes approximately 400 specimens
daily comprising anticoagulation, general haemostasis,
thrombophilia and specialist haemostasis investigations. The
laboratory supports the specialist clinical haemostasis practice at
UHBristol with a wide repertoire of specialist haemostasis
investigations that are appropriate for the regional clinical
haemostasis practice at UHBristol. The Haemostasis laboratory has
now developed an active programme of clinical and translational
coagulation and platelet biology research enables through major
funding from the NIHR and British Heart Foundation.
Haemostasis Consultative Service:
The department also provides a liaison haemostasis service to
paediatric colleagues within UHBristol and other SW regional
centres. This clinical work comprises the clinical evaluation of
and advice on the management of patients with bleeding disorders,
venous thrombosis and complex anticoagulation problems. Much of
this clinical role involves close interaction with clinicians from
the paediatric and neonatal intensive care and cardiac units within
UHBristol.
