Projects and Publications
Projects
Paediatric neuroimaging
Bristol is a specialist centre for
paediatric brain surgery, particularly in epilepsy and Moya Moya
syndrome, and Nuclear Medicine Physics has
developed specialised clinical
imaging and software to aid surgical planning.
SPECT/CT in emphysema
In recent years new treatments for acute emphysema have been
developed. In addition to surgery, less invasive methods involving
the endoscopic insertion of valves and coils have been used.
Alongside this, Nuclear Medicine Physics have supported the use of
simultaneous ventilation-perfusion SPECT/CT, and have carried out
studies to investigate the added impact of quantification of these
studies on treatment planning.
Renal imaging
Nuclear medicine renal imaging has been used for many years to
investigate the effects of surgery. We are supporting radiologists
and surgeons in carrying out further investigation of novel
techniques.
Optimising SPECT/CT imaging
Bristol has recently acquired a state of the art nuclear
medicine computer system, so we are involved in optimising the
reconstruction methods used and introducing routine quantification
of imaging, which will help with monitoring the progress of
diseases such as cancer.
Treatment planning for Molecular
Radiotherapy
Treating cancer with radionuclides is currently having a massive
increase, but the methods for optimising the dose given are in
their infancy compared with external beam radiotherapy. We have
recently taken part in the first UK trial involving multi-centre
calibration of gamma cameras for dosimetry, and are planning to
join other trials of imaging for Molecular Radiotherapy
planning.
Publications
Robin B. Holmes, Ian S. Negus, Sophie J.
Wiltshire, Gareth C. Thorne, Peter Young, The
Alzheimer's Disease Neuroimaging Initiative Creation of an
anthropomorphic CT head phantom for verification of image
segmentation, Medical Physics, 2020
Gregory, Rebecca; Murray, Iain; Gear, Jonathan; Leek,
Francesca; Chittenden, Sarah; Fenwick, Andrew ; Wevrett, Jill;
Scuffham, James; Tipping, Jill; Murby, Brian; Jeans, Steve;
Stuffins, Martha; Michopoulou, Sofia; Guy, Matthew; Morgan, Darren;
Hallam, Aida; Hall, David; Polydor, Heather; Brown, Colin; Gillen,
Gerry; Brown, Sarah; Wadsley, Jonathan; Flux, Glenn Standardised
Quantitative Radioiodine SPECT/CT Imaging for Multicentre Dosimetry
Trials in Molecular Radiotherapy Article reference: 2019 Phys. Med.
Biol. 64 245013.
'Over a Decade's experience in F-15 diuretic renography
and OE quantification'. A Nawwar, F. Zananiri, N. Assaf, M.Darby.
Nuc. Med. Comm. 2019 40(4):74.
'Standardisation of F-5 renography wi renal output
efficiency'. N. Assaf, A. Nawwar,, I. Laurence, F. Zananiri,
M. Darby. (European Association of Nuclear Medicine
Congress, Vienna 2017). Eur J Nuc Med 29(1)1 S355.
D. O. Hall, L. Armstrong, A. Demmery, J.
Kabala Quantification of Ga67 in Necrotising Otitis Externa
Eur J Nucl Med Mol Imaging (2016) 43 (Suppl
1):S588
David Hall, Aline Demmery, Julian Kabala.
Optimising Quantitative SPECT in Condylar Hyperplasia.
Eur J Nucl Med Mol Imaging (2015) (Suppl 1).
'North Bristol Trust's early experience with a small
footprint, triple head, solid state dedicated cardiac camera'. F.
Zananiri, I Laurence. Presentation at Annual South West Nuclear
Medicine meeting 2015.
